DING proteins from phylogenetically different species share high degrees of sequence and structure homology and block transcription of HIV-1 LTR promoter.

DING proteins from phylogenetically different species share high degrees of sequence and structure homology and block transcription of HIV-1 LTR promoter.

Independent research groups reported that DING protein homologues isolated from bacterial, plant and human cells demonstrate the anti-HIV-1 activity. This might indicate that diverse organisms utilize a DING-mediated broad-range protective innate immunity response to pathogen invasion, and that this...

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Bibliographic Details
Main Authors: Rakhee Sachdeva, Nune Darbinian, Kamel Khalili, Shohreh Amini, Daniel Gonzalez, Ahmed Djeghader, Eric Chabriére, Andrew Suh, Ken Scott, Malgorzata Simm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3735540?pdf=render

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http://europepmc.org/articles/PMC3735540?pdf=render

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