Restoring Wnt signaling in a hormone-simulated postpartum depression model remediated imbalanced neurotransmission and depressive-like behaviors

Restoring Wnt signaling in a hormone-simulated postpartum depression model remediated imbalanced neurotransmission and depressive-like behaviors

Abstract Background Postpartum depression (PPD) is a prevalent mental disorder that negatively impacts mothers and infants. The mechanisms of vulnerability to affective illness in the postpartum period remain largely unknown. Drastic fluctuations in reproductive hormones during the perinatal period...

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Bibliographic Details
Main Authors: Binglu Ye, Yawei Yuan, Rui Liu, Haitao Zhou, Yujie Li, Zhihao Sheng, Tianyu Li, Bing Zhang, Zhendong Xu, Yang Li, Zhiqiang Liu
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Molecular Medicine
Subjects:
Postpartum depression (PPD)
Neurotransmission
Hippocampus
CA1
Wnt signaling
Online Access:https://doi.org/10.1186/s10020-023-00697-4

Internet

https://doi.org/10.1186/s10020-023-00697-4

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