Morphological and Immunophenotypical Changes of Human Bone Marrow Adipocytes in Marrow Metastasis and Myelofibrosis

Morphological and Immunophenotypical Changes of Human Bone Marrow Adipocytes in Marrow Metastasis and Myelofibrosis

The bone marrow adipose tissue constitutes more than two-thirds of the bone marrow volume in adult life and is known to have unique metabolic and functional properties. In neoplastic disorders, bone marrow adipocytes (BMAds) contribute to create a favorable microenvironment to survival and prolifera...

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Bibliographic Details
Main Authors: Michele Dello Spedale Venti, Biagio Palmisano, Samantha Donsante, Giorgia Farinacci, Flavia Adotti, Ilenia Coletta, Marta Serafini, Alessandro Corsi, Mara Riminucci
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
bone marrow
marrow metastasis
myeloproliferative neoplasia
myelofibrosis
bone marrow adipose tissue
bone marrow adipocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.882379/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.882379/full

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