Modulation of Retinoic Acid Receptor Signaling Pathway via All-Trans Retinoic Acid in Merkel Cell Carcinoma Cells

The biological activity of retinoic acid or all-trans retinoic acid (ATRA) is mediated by retinoic receptors, which are ligand-dependent transcription factors that activate genes crucial for cell differentiation. Dysregulations of retinoic receptor signaling pathway led to carcinogenesis. A strong i...

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Bibliographic Details
Main Authors: John Charles Rotondo, Chiara Mazziotta, Giampaolo Morciano, Christian Felice Cervellera, Giada Badiale, Giulia Tonnini, Giulia Di Mauro, Paolo Pinton, Antoine Touzé, Pauline Gaboriaud, Mauro Tognon, Fernanda Martini
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biology and Life Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9976/21/1/27