Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand

Abstract Malaria remains a public health problem in Thailand, especially along its borders where highly mobile populations can contribute to persistent transmission. This study aimed to determine resistant genotypes and phenotypes of 112 Plasmodium falciparum isolates from patients along the Thai-Ca...

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Main Authors: Nonlawat Boonyalai, Chatchadaporn Thamnurak, Piyaporn Sai-ngam, Winita Ta-aksorn, Montri Arsanok, Nichapat Uthaimongkol, Siratchana Sundrakes, Sorayut Chattrakarn, Chaiyaporn Chaisatit, Chantida Praditpol, Watcharintorn Fagnark, Kirakarn Kirativanich, Suwanna Chaorattanakawee, Pattaraporn Vanachayangkul, Paphavee Lertsethtakarn, Panita Gosi, Darunee Utainnam, Wuttikon Rodkvamtook, Worachet Kuntawunginn, Brian A. Vesely, Michele D. Spring, Mark M. Fukuda, Charlotte Lanteri, Douglas Walsh, David L. Saunders, Philip L. Smith, Mariusz Wojnarski, Narongrid Sirisopana, Norman C. Waters, Krisada Jongsakul, Jariyanart Gaywee
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92735-6