Aberrant CD40-induced NF-κB activation in human lupus B lymphocytes.

Aberrant CD40-induced NF-κB activation in human lupus B lymphocytes.

Auto-reactive B lymphocytes and its abnormal CD40 signaling play important roles in the pathogenesis of systemic lupus erythematosus (SLE). In this study, we analyzed CD40 expression and CD40/CD154 induced activation of NF-κB signaling pathway in B cells from SLE patients. B cells from healthy volun...

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Bibliographic Details
Main Authors: Wen Zhang, Qun Shi, Xiaotian Xu, Hua Chen, Wei Lin, Fengchun Zhang, Xiaofeng Zeng, Xuan Zhang, Denian Ba, Wei He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3428310?pdf=render

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http://europepmc.org/articles/PMC3428310?pdf=render

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