JNK Signalling Regulates Self-Renewal of Proliferative Urine-Derived Renal Progenitor Cells via Inhibition of Ferroptosis

JNK Signalling Regulates Self-Renewal of Proliferative Urine-Derived Renal Progenitor Cells via Inhibition of Ferroptosis

With a global increase in chronic kidney disease patients, alternatives to dialysis and organ transplantation are needed. Stem cell-based therapies could be one possibility to treat chronic kidney disease. Here, we used multipotent urine-derived renal progenitor cells (UdRPCs) to study nephrogenesis...

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Bibliographic Details
Main Authors: Lisa Nguyen, Leonie Thewes, Michelle Westerhoff, Wasco Wruck, Andreas S. Reichert, Carsten Berndt, James Adjaye
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
JNK signalling
urine stem cells
self-renewal
ferroptosis
cell death
mitochondrial metabolism
Online Access:https://www.mdpi.com/2073-4409/12/17/2197

Internet

https://www.mdpi.com/2073-4409/12/17/2197

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