Renal Fibrosis in Murine Obstructive Nephropathy Is Attenuated by Depletion of Monocyte Lineage, Not Dendritic Cells

Renal Fibrosis in Murine Obstructive Nephropathy Is Attenuated by Depletion of Monocyte Lineage, Not Dendritic Cells

Abstract.: The role of renal dendritic cells (DCs) in renal fibrosis is unknown. The present study was conducted to examine the relative role of renal DCs and macrophages in the development of renal fibrosis in murine obstructive nephropathy. CD11c-diphtheria toxin receptor (DTR) transgenic mice and...

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Bibliographic Details
Main Authors: Yuichi Machida, Koichiro Kitamoto, Yasukatsu Izumi, Masayuki Shiota, Junji Uchida, Yukimi Kira, Tatsuya Nakatani, Katsuyuki Miura
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319308242

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http://www.sciencedirect.com/science/article/pii/S1347861319308242

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