Impact of mRNA-Assessed Molecular Subtype Conversion, Intact and Apoptotic Circulating Tumor Cells on Survival of Metastatic Breast Cancer Patients: Proof of Principle

Impact of mRNA-Assessed Molecular Subtype Conversion, Intact and Apoptotic Circulating Tumor Cells on Survival of Metastatic Breast Cancer Patients: Proof of Principle

Breast cancers (BC) can mutate, allowing metastatic tumors (MT) to sometimes differ to primary tumors (PT) in gene expression. Despite contemporary metastatic breast cancer (MBC) therapy, subtype conversion seems prognostically disadvantageous. We strived to determine the influence of mRNA-assessed...

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Bibliographic Details
Main Authors: Stefan Stefanovic, Thomas M. Deutsch, Ralph Wirtz, Andreas Hartkopf, Peter Sinn, Maximilian Kohler, Jan Hofmann, Sanja Bankovic, Katja Vassilev, Marc Sütterlin, Andreas Schneeweiss, Markus Wallwiener
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Diagnostics
Subjects:
breast cancer
circulating tumor cells
intrinsic subtype
biomarker conversion
survival
RT-qPCR
Online Access:https://www.mdpi.com/2075-4418/10/6/369

Internet

https://www.mdpi.com/2075-4418/10/6/369

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