RAS Signaling in Colorectal Carcinomas through Alteration of RAS, RAF, NF1, and/or RASSF1A

RAS Signaling in Colorectal Carcinomas through Alteration of RAS, RAF, NF1, and/or RASSF1A

More than half of all colorectal carcinomas are known to exhibit an activated mitogen-activated protein kinase pathway. The NF1 gene, a negative regulator of KRAS, has not previously been examined in a series of colorectal cancer. In the present study, primary colorectal carcinomas stratified accord...

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Bibliographic Details
Main Authors: Terje Ahlquist, Irene Bottillo, Stine A. Danielsen, Gunn I. Meling, Torleiv O. Rognum, Guro E. Lind, Bruno Dallapiccola, Ragnhild A. Lothe
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800061

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http://www.sciencedirect.com/science/article/pii/S1476558608800061

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