The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes Mellitus
Background: High-sensitivity C-reactive protein (hs-CRP), and homocysteine increase along with inflammation in type 2 diabetes mellitus (T2DM). The antioxidant properties of sumac might affect homocysteine and hs-CRP levels. We aimed to examine the effects of sumac powder (Rhus Coriaria L) on homocy...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2024-03-01
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| Series: | International Journal of Nutrition Sciences |
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| Online Access: | https://ijns.sums.ac.ir/article_49845_d0eae05d02c07d074ee11895f4938370.pdf |
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| author | Azadeh Nadjarzadeh Mohammad Reza Fattahi Fatemeh Moghtaderi Alireza Vahidi Salimeh Hajiahmadi Mohammad Ali Mohsenpour |
| author_facet | Azadeh Nadjarzadeh Mohammad Reza Fattahi Fatemeh Moghtaderi Alireza Vahidi Salimeh Hajiahmadi Mohammad Ali Mohsenpour |
| author_sort | Azadeh Nadjarzadeh |
| collection | DOAJ |
| description | Background: High-sensitivity C-reactive protein (hs-CRP), and homocysteine increase along with inflammation in type 2 diabetes mellitus (T2DM). The antioxidant properties of sumac might affect homocysteine and hs-CRP levels. We aimed to examine the effects of sumac powder (Rhus Coriaria L) on homocysteine and hs-CRP in patients with T2DM.Methods: In a single-blinded, randomized controlled clinical trial, conducted in Ardekan city, Yazd, Iran; 60 patients with T2DM were randomly divided into 2 groups to consume either low fat yogurt alone in the control group or along with 6 (2×3 grams) grams of sumac powder daily in the intervention group, for 3 months. Fasting blood samples were used to analyze the fasting blood sugar (FBS), serum homocysteine, and hs-CRP at the baseline and after 90 days. P values <0.05 were considered statistically significant.Results: Fifty-eight individuals (intervention n=30, control n=28) with a mean age of 52.30±7.05 years in the intervention, and 51.61±7.07 years in the control group, finished the study. No significant differences were seen for FBS (p=0.94) and homocysteine (p=0.69) changes between the groups; but hs-CRP changes were significantly different between the groups (p=0.03).Conclusion: Daily consumption of sumac powder for 3 months may not have a reducing effect on FBS and serum homocysteine. This is while sumac may prevent increment of hs-CRP in patients with T2DM. |
| first_indexed | 2024-03-07T16:48:39Z |
| format | Article |
| id | doaj.art-e576ba59790d4b0a8537a6e1d27647ff |
| institution | Directory Open Access Journal |
| issn | 2538-1873 2538-2829 |
| language | English |
| last_indexed | 2024-03-07T16:48:39Z |
| publishDate | 2024-03-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | International Journal of Nutrition Sciences |
| spelling | doaj.art-e576ba59790d4b0a8537a6e1d27647ff2024-03-03T06:20:14ZengShiraz University of Medical SciencesInternational Journal of Nutrition Sciences2538-18732538-28292024-03-0191717910.30476/ijns.2024.100116.126849845The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes MellitusAzadeh Nadjarzadeh0Mohammad Reza Fattahi1Fatemeh Moghtaderi2Alireza Vahidi3Salimeh Hajiahmadi4Mohammad Ali Mohsenpour5Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranNutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranNutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranHerbal Medicine Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranNutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranNutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranBackground: High-sensitivity C-reactive protein (hs-CRP), and homocysteine increase along with inflammation in type 2 diabetes mellitus (T2DM). The antioxidant properties of sumac might affect homocysteine and hs-CRP levels. We aimed to examine the effects of sumac powder (Rhus Coriaria L) on homocysteine and hs-CRP in patients with T2DM.Methods: In a single-blinded, randomized controlled clinical trial, conducted in Ardekan city, Yazd, Iran; 60 patients with T2DM were randomly divided into 2 groups to consume either low fat yogurt alone in the control group or along with 6 (2×3 grams) grams of sumac powder daily in the intervention group, for 3 months. Fasting blood samples were used to analyze the fasting blood sugar (FBS), serum homocysteine, and hs-CRP at the baseline and after 90 days. P values <0.05 were considered statistically significant.Results: Fifty-eight individuals (intervention n=30, control n=28) with a mean age of 52.30±7.05 years in the intervention, and 51.61±7.07 years in the control group, finished the study. No significant differences were seen for FBS (p=0.94) and homocysteine (p=0.69) changes between the groups; but hs-CRP changes were significantly different between the groups (p=0.03).Conclusion: Daily consumption of sumac powder for 3 months may not have a reducing effect on FBS and serum homocysteine. This is while sumac may prevent increment of hs-CRP in patients with T2DM.https://ijns.sums.ac.ir/article_49845_d0eae05d02c07d074ee11895f4938370.pdfsumacrhus coriariahomocysteinec-reactive proteindiabetes mellitus |
| spellingShingle | Azadeh Nadjarzadeh Mohammad Reza Fattahi Fatemeh Moghtaderi Alireza Vahidi Salimeh Hajiahmadi Mohammad Ali Mohsenpour The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes Mellitus International Journal of Nutrition Sciences sumac rhus coriaria homocysteine c-reactive protein diabetes mellitus |
| title | The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes Mellitus |
| title_full | The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes Mellitus |
| title_fullStr | The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes Mellitus |
| title_full_unstemmed | The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes Mellitus |
| title_short | The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type 2 Diabetes Mellitus |
| title_sort | effect of sumac powder rhus coriaria l on homocysteine and high sensitivity c reactive protein in patients with type 2 diabetes mellitus |
| topic | sumac rhus coriaria homocysteine c-reactive protein diabetes mellitus |
| url | https://ijns.sums.ac.ir/article_49845_d0eae05d02c07d074ee11895f4938370.pdf |
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