Fluorescence In Vivo Hybridization (FIVH) for Detection of Helicobacter pylori Infection in a C57BL/6 Mouse Model.

INTRODUCTION:In this study, we applied fluorescence in vivo hybridization (FIVH) using locked nucleic acid (LNA) probes targeting the bacterial rRNA gene for in vivo detection of H. pylori infecting the C57BL/6 mouse model. A previously designed Cy3_HP_LNA/2OMe_PS probe, complementary to a sequence...

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Bibliographic Details
Main Authors: Sílvia Fontenete, Marina Leite, Davie Cappoen, Rita Santos, Chris Van Ginneken, Céu Figueiredo, Jesper Wengel, Paul Cos, Nuno Filipe Azevedo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4743915?pdf=render