Familial Hypercholesterolemia and Acute Coronary Syndromes: The Microbiota–Immunity Axis in the New Diagnostic and Prognostic Frontiers

Familial Hypercholesterolemia and Acute Coronary Syndromes: The Microbiota–Immunity Axis in the New Diagnostic and Prognostic Frontiers

Familial hypercholesterolemia is a common genetic disorder with a propensity towards early onset of atherosclerotic cardiovascular disease (CVD). The main goal of therapy is to reduce the LDL cholesterol and the current treatment generally consists of statin, ezetimibe and PCSK9 inhibitors. Unfortun...

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Bibliographic Details
Main Authors: Andrea Piccioni, Elena Niccolai, Gloria Rozzi, Giacomo Spaziani, Christian Zanza, Marcello Candelli, Marcello Covino, Antonio Gasbarrini, Francesco Franceschi, Amedeo Amedei
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pathogens
Subjects:
familial hypercholesterolemia
LDL
cardiovascular disease
atherosclerosis
coagulation
gut microbiota
Online Access:https://www.mdpi.com/2076-0817/12/4/627

Internet

https://www.mdpi.com/2076-0817/12/4/627

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