Andrographolide nanophytosomes exhibit enhanced cellular delivery and pro-apoptotic activities in HepG2 liver cancer cells

Andrographolide nanophytosomes exhibit enhanced cellular delivery and pro-apoptotic activities in HepG2 liver cancer cells

AbstractAndrographolide (AG), a major active constituent of Andrographis paniculata, is known to hinder proliferation of several types of cancer cells. However, its poor solubility and cellular permeability restrict its use in clinical applications. In this study, AG-loaded phytosomes (AG-PTMs) were...

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Bibliographic Details
Main Authors: Thikryat Neamatallah, Azizah M. Malebari, Abdulmohsin J. Alamoudi, Syed Nazreen, Mohammad Mahboob Alam, Hawazen H. Bin-Melaih, Osama A. Abuzinadah, Shaimaa M. Badr-Eldin, Gharam Alhassani, Lamar Makki, Mohammed Z. Nasrullah
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Drug Delivery
Subjects:
Andrographolide
phytosomes
HepG2 cells
apoptosis
liver cancer
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2023.2174209

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https://www.tandfonline.com/doi/10.1080/10717544.2023.2174209

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