Preclinical evaluation of a commercially available biofilm disrupting wound lavage for musculoskeletal trauma

Abstract Background Treatment of open fractures remains a significant challenge in trauma care as these fractures are accompanied by extensive soft tissue damage, exposing the wound site to contaminants and increasing infection risk. Formation of biofilm, a capsule-like environment that acts as a ba...

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Bibliographic Details
Main Authors: Michael E. Whitely, Sarah M. Helms, Preeti J. Muire, Alicia L. Lofgren, Rebecca A. Lopez, Joseph C. Wenke
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-022-03199-x