An emerging role for microRNA in the regulation of endothelin-1

Endothelin-1 (ET-1) is a peptide signaling molecule serving diverse functions in many different tissues such as the vasculature and the kidney. The primary mechanism thought to control ET-1 bioavailability is the rate of transcription from the ET-1 gene (EDN1), but recent research suggests that EDN1...

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Bibliographic Details
Main Authors: Mollie E Jacobs, Charles S Wingo, Brian D Cain
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00022/full