Progranulin deficiency exacerbates cardiac remodeling after myocardial infarction
Abstract Myocardial infarction (MI) is a lethal disease that causes irreversible cardiomyocyte death and subsequent cardiovascular remodeling. We have previously shown that the administration of recombinant progranulin (PGRN) protects against myocardial ischemia and reperfusion injury. However, the...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-10-01
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Series: | FASEB BioAdvances |
Subjects: | |
Online Access: | https://doi.org/10.1096/fba.2023-00084 |