Progranulin deficiency exacerbates cardiac remodeling after myocardial infarction

Progranulin deficiency exacerbates cardiac remodeling after myocardial infarction

Abstract Myocardial infarction (MI) is a lethal disease that causes irreversible cardiomyocyte death and subsequent cardiovascular remodeling. We have previously shown that the administration of recombinant progranulin (PGRN) protects against myocardial ischemia and reperfusion injury. However, the...

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Bibliographic Details
Main Authors:	Takahiro Sasaki, Yoshiki Kuse, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara
Format:	Article
Language:	English
Published:	Wiley 2023-10-01
Series:	FASEB BioAdvances
Subjects:	macrophage myocardial infarction progranulin
Online Access:	https://doi.org/10.1096/fba.2023-00084

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