Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis

Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis

Human parechovirus 3 (HPeV3) can cause severe central nervous system infections and is a major cause of neonatal sepsis. Here the authors determine the structure of HPeV3 that provides a high-resolution view of the capsid’s organization and shows multiple interactions of the RNA genome with coat pro...

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Bibliographic Details
Main Authors: Shabih Shakeel, Brenda M. Westerhuis, Ausra Domanska, Roman I. Koning, Rishi Matadeen, Abraham J. Koster, Arjen Q. Bakker, Tim Beaumont, Katja C. Wolthers, Sarah J. Butcher
Format: Article
Language:English
Published: Nature Portfolio 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11387

Internet

https://doi.org/10.1038/ncomms11387

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