Propranolol-Loaded Trehalosome as Antiproliferative Agent for Treating Skin Cancer: Optimization, Cytotoxicity, and In Silico Studies

Propranolol-Loaded Trehalosome as Antiproliferative Agent for Treating Skin Cancer: Optimization, Cytotoxicity, and In Silico Studies

This study aims at preparing propranolol-loaded trehalosomes (a trehalose-coated liposome) to be used as an antiproliferative agent for treating skin cancer. A factorial design was used to select the optimum formula, where trehalose, lecithin, and Tween 80 levels were studied. A total of 24 runs wer...

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Bibliographic Details
Main Authors: Mona K. Younis, Yara E. Elakkad, Rasha R. Fakhr Eldeen, Isra H. Ali, Islam A. Khalil
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
propranolol
trehalosomes
drug repurposing
skin cancer
Online Access:https://www.mdpi.com/1999-4923/15/8/2033

Internet

https://www.mdpi.com/1999-4923/15/8/2033

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