Ignition of Small Molecule Inhibitors in Friedreich's Ataxia with Explainable Artificial Intelligence

Ignition of Small Molecule Inhibitors in Friedreich's Ataxia with Explainable Artificial Intelligence

Iron (Fe) chelating medicines and Histone deacetylase (HDAC) inhibitors are two therapy options for hereditary Friedreich's Ataxia that have been shown to improve clinical results (FA). Fe chelation molecules can minimize the quantity of stored Fe, and HDAC inhibitors can boost the expression o...

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Bibliographic Details
Main Authors: Kevser Kübra Kirboğa, Ecir Uğur Küçüksille, Utku Kose
Format: Article
Language:English
Published: EduSoft publishing 2023-10-01
Series:Brain: Broad Research in Artificial Intelligence and Neuroscience
Subjects:
explainable artificial intelligence, friedreich ataxia, predictive accuracy, quantitative structure-activity relationship, qsar, shapley values.
Online Access:https://www.edusoft.ro/brain/index.php/brain/article/view/1427

Internet

https://www.edusoft.ro/brain/index.php/brain/article/view/1427

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