Asthma exacerbations and eosinophilia in the UK Biobank: a genome-wide association study

Background Asthma exacerbations reflect disease severity, affect morbidity and mortality, and may lead to declining lung function. Inflammatory endotypes (e.g. T2-high (eosinophilic)) may play a key role in asthma exacerbations. We aimed to assess whether genetic susceptibility underlies asthma exac...

Full description

Bibliographic Details
Main Authors: Ahmed Edris, Kirsten Voorhies, Sharon M. Lutz, Carlos Iribarren, Ian Hall, Ann Chen Wu, Martin Tobin, Katherine Fawcett, Lies Lahousse
Format: Article
Language:English
Published: European Respiratory Society 2024-01-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/10/1/00566-2023.full