Image-guided radiotherapy in an orthotopic mouse model of rectal cancer

Summary: Radiobiology research in rectal cancer has been limited to cell lines, patient-derived organoids (PDOs), or xenografts. Here, we describe a protocol which recapitulates more efficiently the complex contributions of the tumor microenvironment. This approach establishes a preclinical mouse mo...

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Bibliographic Details
Main Authors: Adele M. Nicolas, Marina Pesic, Franz Rödel, Emmanouil Fokas, Florian R. Greten
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722006293