Post-translational modifications of fibrinogen: implications for clotting, fibrin structure and degradation

Post-translational modifications of fibrinogen: implications for clotting, fibrin structure and degradation

Abstract Fibrinogen, a blood plasma protein with a key role in hemostasis and thrombosis, is highly susceptible to post-translational modifications (PTMs), that significantly influence clot formation, structure, and stability. These PTMs, which include acetylation, amidation, carbamylation, citrulli...

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Bibliographic Details
Main Authors: Francesca Nencini, Alessandra Bettiol, Flavia Rita Argento, Serena Borghi, Elvira Giurranna, Giacomo Emmi, Domenico Prisco, Niccolò Taddei, Claudia Fiorillo, Matteo Becatti
Format: Article
Language:English
Published: Springer 2024-10-01
Series:Molecular Biomedicine
Subjects:
Fibrin
Fibrinogen
Post-translational modifications
Thrombosis
Online Access:https://doi.org/10.1186/s43556-024-00214-x

Internet

https://doi.org/10.1186/s43556-024-00214-x

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