Additive effect of 5-HT2C and CB1 receptor blockade on the regulation of sleep–wake cycle
Abstract Background Previous data show that serotonin 2C (5-HT2C) and cannabinoid 1 (CB1) receptors have a role in the modulation of sleep–wake cycle. Namely, antagonists on these receptors promoted wakefulness and inhibited rapid eye movement sleep (REMS) in rodents. The interaction of these recept...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | BMC Neuroscience |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12868-019-0495-7 |