In Vivo Evaluation of Praziquantel-Loaded Solid Lipid Nanoparticles against <i>S. mansoni</i> Infection in Preclinical Murine Models

In Vivo Evaluation of Praziquantel-Loaded Solid Lipid Nanoparticles against <i>S. mansoni</i> Infection in Preclinical Murine Models

This study aimed to develop and assess the long-term stability of drug-loaded solid lipid nanoparticles (SLNs). The SLNs were designed to extend the release profile, overcome the problems of bioavailability and solubility, investigate toxicity, and improve the antischistosomal efficacy of praziquant...

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Bibliographic Details
Main Authors: Tayo A. Adekiya, Pradeep Kumar, Pierre P. D. Kondiah, Philemon Ubanako, Yahya E. Choonara
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
praziquantel
solid lipid nanoparticles
Compritol ATO 888
soy lecithin
<i>S. mansoni</i>
schistosomiasis
Online Access:https://www.mdpi.com/1422-0067/23/16/9485

Internet

https://www.mdpi.com/1422-0067/23/16/9485

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