Therapeutic effect and transcriptome-methylome characteristics of METTL3 inhibition in liver hepatocellular carcinoma

Abstract Methyltransferase-like 3 (METTL3) is the key subunit of methyltransferase complex responsible for catalyzing N6-methyladenosine (m6A) modification on mRNA, which is the most prevalent post-transcriptional modification in eukaryotes. In this study, we utilized online databases to analyze the...

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Bibliographic Details
Main Authors: Qingbin Liu, Jingjing Qi, Weiyang Li, Xinchen Tian, Jiaqi Zhang, Fen Liu, Xiulian Lu, Hengchang Zang, Chenqiao Liu, Changlin Ma, Yong Yu, Shulong Jiang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-03096-1