Subcellular Targeting of the Euplotes raikovi Kinase Er-MAPK1, as Revealed by Expression in Different Cell Systems

Subcellular Targeting of the Euplotes raikovi Kinase Er-MAPK1, as Revealed by Expression in Different Cell Systems

In the ciliate Euplotes raikovi, a 631-amino acid Er-MAPK1 protein kinase was found to localize in nucleoli of the transcriptionally active nucleus (macronucleus) and act as a key component of an autocrine, cell-growth promoting self-signaling mechanism. While its 283-amino acid N-terminal domain in...

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Bibliographic Details
Main Authors: Annalisa Candelori, Takaharu G. Yamamoto, Masaaki Iwamoto, Maura Montani, Augusto Amici, Adriana Vallesi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ciliated protozoa
protein kinase
heterologous gene expression
GFP-fusion proteins
nuclear and ciliary protein kinase
ICK-related kinase
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00244/full

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https://www.frontiersin.org/article/10.3389/fcell.2019.00244/full

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