Galantamine protects against lipopolysaccharide-induced acute lung injury in rats

Galantamine protects against lipopolysaccharide-induced acute lung injury in rats

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Lipopolysaccharide (LPS)-induced endotoxemia triggers the secretion of proinflammatory cytokines and can cause acute lung injury (ALI). The high mobility group box 1 (HMGB1) protein plays an important role as a late mediator of sepsis and ALI. Galantamine (GAL) is a central acetylcholinesterase inhi...

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Bibliographic Details
Main Authors: G. Li, CL. Zhou, QS. Zhou, HD. Zou
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Galantamine
Acute lung injury
Lipopolysaccharide
HMGB1
Online Access:http://www.scielo.br/pdf/bjmbr/v49n2/1414-431X-bjmbr-1414-431X20155008.pdf

Internet

http://www.scielo.br/pdf/bjmbr/v49n2/1414-431X-bjmbr-1414-431X20155008.pdf

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