Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR

Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR

Site-directed RNA editing (SDRE) technologies have great potential for treating genetic diseases caused by point mutations. Our group and other researchers have developed SDRE methods utilizing adenosine deaminases acting on RNA (ADARs) and guide RNAs recruiting ADARs to target RNAs bearing point mu...

Full description

Bibliographic Details
Main Authors: Tetsuto Tohama, Matomo Sakari, Toshifumi Tsukahara
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
RNA editing
site-directed RNA editing
adenosine deaminases acting on RNA
MS2 system
single construct
MS2-ADAR
Online Access:https://www.mdpi.com/1422-0067/21/14/4943

Internet

https://www.mdpi.com/1422-0067/21/14/4943

Similar Items