HAMLET binding to α-actinin facilitates tumor cell detachment.

HAMLET binding to α-actinin facilitates tumor cell detachment.

Cell adhesion is tightly regulated by specific molecular interactions and detachment from the extracellular matrix modifies proliferation and survival. HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a protein-lipid complex with tumoricidal activity that also triggers tumor cell detac...

Full description

Bibliographic Details
Main Authors: Maria Trulsson, Hao Yu, Lennart Gisselsson, Yinxia Chao, Alexander Urbano, Sonja Aits, Ann-Kristin Mossberg, Catharina Svanborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21408150/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21408150/?tool=EBI

Similar Items