Role of integrins in the development of fibrosis in the trabecular meshwork

Role of integrins in the development of fibrosis in the trabecular meshwork

Primary open angle glaucoma (POAG) is a progressive and chronic disease exhibiting many of the features of fibrosis. The extracellular matrix (ECM) in the trabecular meshwork (TM) undergoes extensive remodeling and enhanced rigidity, resembling fibrotic changes. In addition, there are changes associ...

Full description

Bibliographic Details
Main Authors: Jennifer A. Faralli, Mark S. Filla, Donna M. Peters
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Ophthalmology
Subjects:
integrins
trabecular meshwork
fibronectin
extracellular matrix
fibrosis
TGFβ2
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2023.1274797/full

Internet

https://www.frontiersin.org/articles/10.3389/fopht.2023.1274797/full

Similar Items