Metabolic engineering of Pseudomonas putida KT2440 to produce anthranilate from glucose

Metabolic engineering of Pseudomonas putida KT2440 to produce anthranilate from glucose

The Pseudomonas putida KT2440 strain was engineered in order to produce anthranilate (oAB, ortho-aminobenzoate), a precursor of the aromatic amino acid tryptophan, from glucose as sole carbon source. To enable the production of the metabolic intermediate oAB, the trpDC operon encoding an anthranilat...

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Bibliographic Details
Main Authors: Jannis eKuepper, Jasmin eDickler, Michael eBiggel, Swantje eBehnken, Gernot eJaeger, Nick eWierckx, Lars M Blank
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Microbiology
Subjects:
Metabolic Engineering
Industrial Biotechnology
Anthranilic acid
Pseudomonas putida KT2440
Aromatic amino acid pathway
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01310/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01310/full

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