Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance.
The evolution of drug resistance is an important process that affects clinical outcomes. Resistance to fluconazole, the most widely used antifungal, is often associated with acquired aneuploidy. Here we provide a longitudinal study of the prevalence and dynamics of gross chromosomal rearrangements,...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-10-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2760147?pdf=render |