Platelet-enhanced apolipoprotein E production by human macrophages: a possible role in atherosclerosis

Cholesterol-loaded human monocyte-derived macrophages increase their production of apolipoprotein E (apoE). Although cholesterol loading is often achieved with modified plasma lipoproteins, macrophages can be loaded also by coculture with platelets. Therefore, the relationship between platelet-media...

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Bibliographic Details
Main Authors: Y Takagi, C A Dyer, L K Curtiss
Format: Article
Language:English
Published: Elsevier 1988-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520384807