Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis

The small GTPase ARF family member ARL15 gene locus is associated in population studies with increased risk of type 2 diabetes, lower adiponectin and higher fasting insulin levels. Previously, loss of ARL15 was shown to reduce insulin secretion in a human β-cell line and loss-of-function mutations a...

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Bibliographic Details
Main Authors: Yixing Wu, Ying Bai, David G. McEwan, Liz Bentley, Dimitra Aravani, Roger D. Cox
Format: Article
Language:English
Published: The Company of Biologists 2021-12-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/10/12/bio058420