New Pyrazolo-Benzimidazole Mannich Bases with Antimicrobial and Antibiofilm Activities

New Pyrazolo-Benzimidazole Mannich Bases with Antimicrobial and Antibiofilm Activities

A new series of pyrazolo-benzimidazole hybrid Mannich bases were synthesized, characterized by <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro cytotoxicity of the new compounds studied on fibroblast cells showed that the newly synthesiz...

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Bibliographic Details
Main Authors: Christina Zalaru, Florea Dumitrascu, Constantin Draghici, Isabela Tarcomnicu, Maria Marinescu, George Mihai Nitulescu, Rodica Tatia, Lucia Moldovan, Marcela Popa, Mariana Carmen Chifiriuc
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antibiotics
Subjects:
pyrazoles
benzimidazoles
hybrid heterocyclic molecules
cytotoxicity
antimicrobial
biofilm formation
Online Access:https://www.mdpi.com/2079-6382/11/8/1094

Internet

https://www.mdpi.com/2079-6382/11/8/1094

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