Histone demethylase KDM3B protects against ferroptosis by upregulating SLC7A11

Ferroptosis is a type of adaptive cell death driven by cellular metabolism and iron‐dependent lipid peroxidation. Though multiple genes (including SLC7A11 and GPX4) have been demonstrated to play key roles in ferroptosis, little is known about the epigenetic regulation of this process. Here, we repo...

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Bibliographic Details
Main Authors: Yishu Wang, Yao Zhao, Haihua Wang, Chengliang Zhang, Meiqi Wang, Yong Yang, Xin Xu, Zhenbo Hu
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12823