MST1 deletion protects β-cells in a mouse model of diabetes
Abstract The pro-apoptotic kinase Mammalian Sterile 20-like kinase 1 (MST1), an integral component of the Hippo pathway, is a key regulator of organ size, stress response, and tissue homeostasis; its aberrant hyperactivation is linked to multiple pathological disorders including diabetes. Here we sh...
Main Authors: | Amin Ardestani, Kathrin Maedler |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-02-01
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Series: | Nutrition & Diabetes |
Online Access: | https://doi.org/10.1038/s41387-022-00186-3 |
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