Redox Balance in β-Thalassemia and Sickle Cell Disease: A Love and Hate Relationship

Redox Balance in β-Thalassemia and Sickle Cell Disease: A Love and Hate Relationship

β-thalassemia and sickle cell disease (SCD) are inherited hemoglobinopathies that result in both quantitative and qualitative variations in the β-globin chain. These in turn lead to instability in the generated hemoglobin (Hb) or to a globin chain imbalance that affects the oxidative environment bot...

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Bibliographic Details
Main Authors: Rayan Bou-Fakhredin, Lucia De Franceschi, Irene Motta, Assaad A. Eid, Ali T. Taher, Maria Domenica Cappellini
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Antioxidants
Subjects:
β-thalassemia
sickle cell disease
oxidative stress
oxidant
antioxidant
redox
Online Access:https://www.mdpi.com/2076-3921/11/5/967

Internet

https://www.mdpi.com/2076-3921/11/5/967

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