Adoptive immunotherapy with natural killer cells from peripheral blood CD34+ stem cells to prevent hepatocellular carcinoma recurrence after curative hepatectomy: a study protocol for an open-label, single-arm phase I study

Adoptive immunotherapy with natural killer cells from peripheral blood CD34+ stem cells to prevent hepatocellular carcinoma recurrence after curative hepatectomy: a study protocol for an open-label, single-arm phase I study

Introduction Hepatocellular carcinoma (HCC) remains a major clinical problem as more than half of these cases recur after radical resection. Natural killer (NK) cells are at the forefront of the innate immune system and attack microcarcinomas and circulating tumour cells. The objective of this study...

Full description

Bibliographic Details
Main Authors: Kenichi Yoshimura, Keiko Ueda, Hiroshi Aikata, Michio Imamura, Reo Kawano, Masahiro Ohira, Tsuyoshi Kobayashi, Yuka Tanaka, Yuki Imaoka, Koki Sato, Koki Imaoka, Ryosuke Nakano, Marlen Doskali, Jinlian Piao, Mayuna Nakamura, Tetsumi Yoshida, Tatsuo Ichinohe, Natsuko Tamura, Taizo Hirata, Naoki Tanimine, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Hideki Ohdan
Format: Article
Language:English
Published: BMJ Publishing Group 2022-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/11/e064526.full

Internet

https://bmjopen.bmj.com/content/12/11/e064526.full

Similar Items