Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82.

G protein-coupled receptors (GPCR) are involved in the regulation of numerous physiological functions. Therefore, GPCR variants may have conferred important selective advantages during periods of human evolution. Indeed, several genomic loci with signatures of recent selection in humans contain GPCR...

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Bibliographic Details
Main Authors: Kathrin M Y Engel, Kristin Schröck, Daniel Teupser, Lesca Miriam Holdt, Anke Tönjes, Matthias Kern, Kerstin Dietrich, Peter Kovacs, Ute Krügel, Holger A Scheidt, Jürgen Schiller, Daniel Huster, Gudrun A Brockmann, Martin Augustin, Joachim Thiery, Matthias Blüher, Michael Stumvoll, Torsten Schöneberg, Angela Schulz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22216272/pdf/?tool=EBI