Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.

Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.

In most transmissible spongiform encephalopathies prions accumulate in the lymphoreticular system (LRS) long before they are detectable in the central nervous system. While a considerable body of evidence showed that B lymphocytes and follicular dendritic cells play a major role in prion colonizatio...

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Bibliographic Details
Main Authors: Rocio Castro-Seoane, Holger Hummerich, Trevor Sweeting, M Howard Tattum, Jacqueline M Linehan, Mar Fernandez de Marco, Sebastian Brandner, John Collinge, Peter-Christian Klöhn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3280992?pdf=render

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http://europepmc.org/articles/PMC3280992?pdf=render

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