NADPH Oxidase (NOX) Targeting in Diabetes: A Special Emphasis on Pancreatic β-Cell Dysfunction

NADPH Oxidase (NOX) Targeting in Diabetes: A Special Emphasis on Pancreatic β-Cell Dysfunction

In type 2 diabetes, metabolic stress has a negative impact on pancreatic β-cell function and survival (T2D). Although the pathogenesis of metabolic stress is complex, an imbalance in redox homeostasis causes abnormal tissue damage and β-cell death due to low endogenous antioxidant expression levels...

Full description

Bibliographic Details
Main Authors: Suma Elumalai, Udayakumar Karunakaran, Jun-Sung Moon, Kyu-Chang Won
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
NADPH oxidase
diabetes mellitus
insulin-secreting cells
oxidative stress
reactive oxygen species
Online Access:https://www.mdpi.com/2073-4409/10/7/1573

Internet

https://www.mdpi.com/2073-4409/10/7/1573

Similar Items