Transient receptor potential melastatin 2 regulates neutrophil extracellular traps formation and delays resolution of neutrophil-driven sterile inflammation

Abstract The formation of neutrophil extracellular traps (NETs) is a process releasing into the extracellular space networks of chromatin fibers decorated with granular proteins. It is implicated in infection-related as well as sterile inflammation. Monosodium urate (MSU) crystals serve as damage-as...

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Bibliographic Details
Main Authors: Xue Cao, Yanhong Li, Yubin Luo, Tianshu Chu, Hang Yang, Ji Wen, Yi Liu, Yi Zhao, Martin Herrmann
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Inflammation
Subjects:
Online Access:https://doi.org/10.1186/s12950-023-00334-1