Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL

Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL

Abstract Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other inflammatory diseases. There is no disease-specific difference in viral strains, and it is unclear how HTLV-1 causes such d...

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Bibliographic Details
Main Authors: Mari Kannagi, Atsuhiko Hasegawa, Yoshiko Nagano, Shuichi Kimpara, Youko Suehiro
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Retrovirology
Subjects:
HTLV-1
ATL
Innate immunity
Acquired immunity
Interferon
IL-10
Online Access:http://link.springer.com/article/10.1186/s12977-019-0484-z

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http://link.springer.com/article/10.1186/s12977-019-0484-z

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