Cancer’s camouflage: Microvesicle shedding from cholesterol-rich tumor plasma membranes might blindfold first-responder immunosurveillance strategies
Intermediary metabolism of tumors is characterized, in part, by a dysregulation of the cholesterol biosynthesis pathway at its rate-controlling enzyme providing the molecular basis for tumor membranes (mitochondria, plasma membrane) to become enriched with cholesterol (Bloch, 1965; Feo et al., 1975;...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-04-01
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Series: | European Journal of Cell Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S017193352200022X |