<i>Neisseria meningitidis</i> Factor H Binding Protein Surface Exposure on <i>Salmonella</i> Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases

<i>Neisseria meningitidis</i> Factor H Binding Protein Surface Exposure on <i>Salmonella</i> Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases

GMMA, outer membrane vesicles resulting from hyperblebbing mutated bacterial strains, are a versatile vaccine platform for displaying both homologous and heterologous antigens. Periplasmic expression is a popular technique for protein expression in the lumen of the blebs. However, the ability of int...

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Bibliographic Details
Main Authors: Francesca Necchi, Giuseppe Stefanetti, Renzo Alfini, Elena Palmieri, Martina Carducci, Roberta Di Benedetto, Fabiola Schiavo, Maria Grazia Aruta, Fabiola Giusti, Ilaria Ferlenghi, Yun Shan Goh, Simona Rondini, Francesca Micoli
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pathogens
Subjects:
GMMA
Salmonella
Neisseria meningitidis
fHbp
Online Access:https://www.mdpi.com/2076-0817/10/6/726

Internet

https://www.mdpi.com/2076-0817/10/6/726

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