Formation of synthetic RNA protein granules using engineered phage-coat-protein -RNA complexes

Condensates composed of RNA and proteins are biologically vital but generally poorly understood. Here, the authors engineer synthetic RNA-protein condensates and show that gel-like condensates form as a result of liquid-gel phase separation in a specific and selective fashion.

Bibliographic Details
Main Authors: Naor Granik, Noa Katz, Or Willinger, Sarah Goldberg, Roee Amit
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34644-4