Aging and Exercise Affect Hippocampal Neurogenesis via Different Mechanisms.

Aging and Exercise Affect Hippocampal Neurogenesis via Different Mechanisms.

The rate of neurogenesis is determined by 1) the number of neural stem/progenitor cells (NSCs), 2) proliferation of NSCs, 3) neuron lineage specification, and 4) survival rate of the newborn neurons. Aging lowers the rate of hippocampal neurogenesis, while exercise (Ex) increases this rate. However,...

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Bibliographic Details
Main Authors: Ting-Ting Yang, Chen-Peng Lo, Pei-Shan Tsai, Shih-Ying Wu, Tzu-Feng Wang, Yun-Wen Chen, Ya-Fen Jiang-Shieh, Yu-Min Kuo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4493040?pdf=render

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http://europepmc.org/articles/PMC4493040?pdf=render

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